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PSD-95 family MAGUKs are essential for anchoring AMPA and NMDA receptor complexes at the postsynaptic density

The postsynaptic density (PSD)-95 family of membrane-associated guanylate kinases (MAGUKs) are major scaffolding proteins at the PSD in glutamatergic excitatory synapses, where they maintain and modulate synaptic strength. How MAGUKs underlie synaptic strength at the molecular level is still not wel...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Chen, Xiaobing, Levy, Jonathan M., Hou, Austin, Winters, Christine, Azzam, Rita, Sousa, Alioscka A., Leapman, Richard D., Nicoll, Roger A., Reese, Thomas S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687590/
https://ncbi.nlm.nih.gov/pubmed/26604311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1517045112
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