In Vivo Detection of Amyloid Plaques by Gadolinium-Stained MRI Can Be Used to Demonstrate the Efficacy of an Anti-amyloid Immunotherapy

Extracellular deposition of β amyloid plaques is an early event associated to Alzheimer’s disease. Here, we have used in vivo gadolinium-stained high resolution (29(∗)29(∗)117 μm(3)) magnetic resonance imaging (MRI) to follow-up in a longitudinal way individual amyloid plaques in APP/PS1 mice and ev...

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Vydáno v:Front Aging Neurosci
Hlavní autoři: Santin, Mathieu D., Vandenberghe, Michel E., Herard, Anne-Sophie, Pradier, Laurent, Cohen, Caroline, Debeir, Thomas, Delzescaux, Thierry, Rooney, Thomas, Dhenain, Marc
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2016
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4802995/
https://ncbi.nlm.nih.gov/pubmed/27047372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2016.00055
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