載入...
Tetravalent Bispecific Tandem Antibodies Improve Brain Exposure and Efficacy in an Amyloid Transgenic Mouse Model
Most antibodies display very low brain exposure due to the blood-brain barrier (BBB) preventing their entry into brain parenchyma. Transferrin receptor (TfR) has been used previously to ferry antibodies to the brain by using different formats of bispecific constructs. Tetravalent bispecific tandem i...
Na minha lista:
| 發表在: | Mol Ther Methods Clin Dev |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society of Gene & Cell Therapy
2020
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7502788/ https://ncbi.nlm.nih.gov/pubmed/33005703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.08.014 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|