The PKR Activator PACT Is Induced by Aβ: Involvement in Alzheimer's Disease

The neuropathological hallmarks of Alzheimer's disease (AD) include senile plaques made of Aβ peptide, neurofibrillary tangles containing hyperphosphorylated tau protein and neuronal loss. The pro‐apoptotic kinase PKR can be activated by Aβ and can phosphorylate tau protein via GSK3β kinase act...

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Dades bibliogràfiques
Publicat a:Brain Pathol
Autors principals: Paquet, Claire, Mouton‐Liger, François, Meurs, Eliane F., Mazot, Pierre, Bouras, Constantin, Pradier, Laurent, Gray, Françoise, Hugon, Jacques
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2011
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029131/
https://ncbi.nlm.nih.gov/pubmed/21790829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2011.00520.x
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