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PKR involvement in Alzheimer’s disease
BACKGROUND: Brain lesions in Alzheimer’s disease (AD) are characterized by Aβ accumulation, neurofibrillary tangles, and synaptic and neuronal vanishing. According to the amyloid cascade hypothesis, Aβ1-42 oligomers could trigger a neurotoxic cascade with kinase activation that leads to tau phosphor...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Alzheimers Res Ther |
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| Κύριοι συγγραφείς: | , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
BioMed Central
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5629792/ https://ncbi.nlm.nih.gov/pubmed/28982375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-017-0308-0 |
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