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PKR involvement in Alzheimer’s disease

BACKGROUND: Brain lesions in Alzheimer’s disease (AD) are characterized by Aβ accumulation, neurofibrillary tangles, and synaptic and neuronal vanishing. According to the amyloid cascade hypothesis, Aβ1-42 oligomers could trigger a neurotoxic cascade with kinase activation that leads to tau phosphor...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Alzheimers Res Ther
Prif Awduron: Hugon, Jacques, Mouton-Liger, François, Dumurgier, Julien, Paquet, Claire
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629792/
https://ncbi.nlm.nih.gov/pubmed/28982375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-017-0308-0
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