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Increased levels of cerebrospinal fluid JNK3 associated with amyloid pathology: links to cognitive decline
BACKGROUND: Alzheimer disease is characterized by cognitive decline, senile plaques of β-amyloid (Aβ) peptides, neurofibrillary tangles composed of hyperphosphorylated τ proteins and neuronal loss. Aβ and τ are useful markers in the cerebrospinal fluid (CSF). C-Jun N-terminal kinases (JNKs) are seri...
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| Publicado no: | J Psychiatry Neurosci |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
8872147 Canada Inc.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4409432/ https://ncbi.nlm.nih.gov/pubmed/25455349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1503/jpn.140062 |
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