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Increased levels of cerebrospinal fluid JNK3 associated with amyloid pathology: links to cognitive decline

BACKGROUND: Alzheimer disease is characterized by cognitive decline, senile plaques of β-amyloid (Aβ) peptides, neurofibrillary tangles composed of hyperphosphorylated τ proteins and neuronal loss. Aβ and τ are useful markers in the cerebrospinal fluid (CSF). C-Jun N-terminal kinases (JNKs) are seri...

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Bibliographische Detailangaben
Veröffentlicht in:J Psychiatry Neurosci
Hauptverfasser: Gourmaud, Sarah, Paquet, Claire, Dumurgier, Julien, Pace, Clarisse, Bouras, Constantin, Gray, Françoise, Laplanche, Jean-Louis, Meurs, Eliane F., Mouton-Liger, François, Hugon, Jacques
Format: Artigo
Sprache:Inglês
Veröffentlicht: 8872147 Canada Inc. 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409432/
https://ncbi.nlm.nih.gov/pubmed/25455349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1503/jpn.140062
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