Novel Molecular Mechanisms in the Development of Non-Alcoholic Steatohepatitis

gan Povero, Davide, Feldstein, Ariel E.
Cyhoeddwyd yn Diabetes Metab J (2016)

Microparticles Release by Adipocytes Act as “Find-Me” Signals to Promote Macrophage Migration

gan Eguchi, Akiko, Mulya, Anny, Lazic, Milos, Radhakrishnan, Deepa, Berk, Michael P., Povero, Davide, Gornicka, Agnieszka, Feldstein, Ariel E.
Cyhoeddwyd yn PLoS One (2015)

Circulating Extracellular Vesicles with Specific Proteome and Liver MicroRNAs Are Potential Biomarkers for Liver Injury in Experimental Fatty Liver Disease

gan Povero, Davide, Eguchi, Akiko, Li, Hongying, Johnson, Casey D., Papouchado, Bettina G., Wree, Alexander, Messer, Karen, Feldstein, Ariel E.
Cyhoeddwyd yn PLoS One (2014)

Caspase 3 inactivation protects against hepatic cell death and ameliorates fibrogenesis in a diet induced NASH model

gan Thapaliya, Samjhana, Wree, Alexander, Povero, Davide, Inzaugarat, Maria Eugenia, Berk, Michael, Dixon, Laura, Papouchado, Bettina G., Feldstein, Ariel E
Cyhoeddwyd yn Dig Dis Sci (2014)

Differential regulation of inflammation and apoptosis in Fas-resistant hepatocyte-specific Bid-deficient mice

gan Lazic, Milos, Eguchi, Akiko, Berk, Michael P., Povero, Davide, Papouchado, Bettina, Mulya, Anny, Johnson, Casey D., Feldstein, Ariel E.
Cyhoeddwyd yn J Hepatol (2014)

ARGINASE 2 DEFICIENCY RESULTS IN SPONTANEOUS STEATOHEPATITIS: A NOVEL LINK BETWEEN INNATE IMMUNE ACTIVATION AND HEPATIC DE NOVO LIPOGENESIS

gan Navarro, Laura A., Wree, Alexander, Povero, Davide, Berk, Michael P., Eguchi, Akiko, Ghosh, Sudakshina, Papouchado, Bettina G., Erzurum, Serpil C., Feldstein, Ariel E.
Cyhoeddwyd yn J Hepatol (2014)

Redox nanoparticles as a novel treatment approach for inflammation and fibrosis associated with nonalcoholic steatohepatitis

gan Eguchi, Akiko, Yoshitomi, Toru, Lazic, Milos, Johnson, Casey D, Vong, Long Binh, Wree, Alexander, Povero, Davide, Papouchado, Bettina G, Nagasaki, Yukio, Feldstein, Ariel E
Cyhoeddwyd yn Nanomedicine (Lond) (2015)

Emricasan, a pan caspase inhibitor, improves survival and portal hypertension in a murine model of common bile-duct ligation

gan Eguchi, Akiko, Koyama, Yukinori, Wree, Alexander, Johnson, Casey D., Nakamura, Ryota, Povero, Davide, Kneiber, David, Tameda, Masahiko, Contreras, Patricia, Spada, Al, Feldstein, Ariel E.
Cyhoeddwyd yn J Mol Med (Berl) (2018)

Reduced Dietary Omega-6 to Omega-3 Fatty Acid Ratio and 12/15-Lipoxygenase Deficiency Are Protective against Chronic High Fat Diet-Induced Steatohepatitis

gan Lazic, Milos, Inzaugarat, Maria Eugenia, Povero, Davide, Zhao, Iris C., Chen, Mark, Nalbandian, Madlena, Miller, Yury I., Cherñavsky, Alejandra C., Feldstein, Ariel E., Sears, Dorothy D.
Cyhoeddwyd 2014

Lipid-Induced Hepatocyte-Derived Extracellular Vesicles Regulate Hepatic Stellate Cells via MicroRNA Targeting Peroxisome Proliferator-Activated Receptor-γ

gan Povero, Davide, Panera, Nadia, Eguchi, Akiko, Johnson, Casey D., Papouchado, Bettina G., de Araujo Horcel, Lucas, Pinatel, Eva M., Alisi, Anna, Nobili, Valerio, Feldstein, Ariel E.
Cyhoeddwyd yn Cell Mol Gastroenterol Hepatol (2015)

Extracellular vesicles released by hepatocytes from gastric infusion model of ALD contain a miRNA barcode that can be detected in blood

gan Eguchi, Akiko, Lazaro, Raul G, Wang, Jiaohong, Kim, Jihoon, Povero, Davide, Willliams, Brandon, Ho, Samuel B, Stärkel, Peter, Schnabl, Bernd, Ohno-Machado, Lucila, Tsukamoto, Hidekazu, Feldstein, Ariel E.
Cyhoeddwyd yn Hepatology (2016)

Lipid-induced toxicity stimulates hepatocytes to release angiogenic microparticles that require Vanin-1 for uptake by endothelial cells

gan Povero, Davide, Eguchi, Akiko, Niesman, Ingrid R., Andronikou, Nektaria, de Mollerat du Jeu, Xavier, Mulya, Anny, Berk, Michael, Lazic, Milos, Thapaliya, Samjana, Parola, Maurizio, Patel, Hemal H., Feldstein, Ariel E.
Cyhoeddwyd 2013

Human induced pluripotent stem cell–derived extracellular vesicles reduce hepatic stellate cell activation and liver fibrosis

gan Povero, Davide, Pinatel, Eva M., Leszczynska, Aleksandra, Goyal, Nidhi P., Nishio, Takahiro, Kim, Jihoon, Kneiber, David, de Araujo Horcel, Lucas, Eguchi, Akiko, Ordonez, Paulina M., Kisseleva, Tatiana, Feldstein, Ariel E.
Cyhoeddwyd yn JCI Insight (2019)

Andrographolide Ameliorates Inflammation and Fibrogenesis and Attenuates Inflammasome Activation in Experimental Non-Alcoholic Steatohepatitis

gan Cabrera, Daniel, Wree, Alexander, Povero, Davide, Solís, Nancy, Hernandez, Alejandra, Pizarro, Margarita, Moshage, Han, Torres, Javiera, Feldstein, Ariel E., Cabello-Verrugio, Claudio, Brandan, Enrique, Barrera, Francisco, Arab, Juan Pablo, Arrese, Marco
Cyhoeddwyd yn Sci Rep (2017)

Characterization and Proteome of Circulating Extracellular Vesicles as Potential Biomarkers for NASH

gan Povero, Davide, Yamashita, Hirokazu, Ren, Wenhua, Subramanian, Mani G., Myers, Robert P., Eguchi, Akiko, Simonetto, Douglas A., Goodman, Zachary D., Harrison, Stephen A., Sanyal, Arun J., Bosch, Jaime, Feldstein, Ariel E.
Cyhoeddwyd yn Hepatol Commun (2020)

Microvesicles released from fat-laden cells promote activation of hepatocellular NLRP3 inflammasome: A pro-inflammatory link between lipotoxicity and non-alcoholic steatohepatitis

gan Cannito, Stefania, Morello, Elisabetta, Bocca, Claudia, Foglia, Beatrice, Benetti, Elisa, Novo, Erica, Chiazza, Fausto, Rogazzo, Mara, Fantozzi, Roberto, Povero, Davide, Sutti, Salvatore, Bugianesi, Elisabetta, Feldstein, Ariel E., Albano, Emanuele, Collino, Massimo, Parola, Maurizio
Cyhoeddwyd yn PLoS One (2017)

Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis

gan Gaul, Susanne, Leszczynska, Aleksandra, Alegre, Fernando, Kaufmann, Benedikt, Johnson, Casey D., Adams, Leon A., Wree, Alexander, Damm, Georg, Seehofer, Daniel, Calvente, Carolina J., Povero, Davide, Kisseleva, Tatiana, Eguchi, Akiko, McGeough, Matthew D., Hoffman, Hal M., Pelegrin, Pablo, Laufs, Ulrich, Feldstein, Ariel E.
Cyhoeddwyd yn J Hepatol (2020)