Human induced pluripotent stem cell–derived extracellular vesicles reduce hepatic stellate cell activation and liver fibrosis

Progression of fibrosis and the development of cirrhosis are responsible for the liver-related morbidity and mortality associated with chronic liver diseases. There is currently a great unmet need for effective antifibrotic strategies. Stem cells play a central role in wound-healing responses to res...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Povero, Davide, Pinatel, Eva M., Leszczynska, Aleksandra, Goyal, Nidhi P., Nishio, Takahiro, Kim, Jihoon, Kneiber, David, de Araujo Horcel, Lucas, Eguchi, Akiko, Ordonez, Paulina M., Kisseleva, Tatiana, Feldstein, Ariel E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675559/
https://ncbi.nlm.nih.gov/pubmed/31184999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.125652
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