PRKCH regulates hematopoietic stem cell function and predicts poor prognosis in acute myeloid leukemia

por Porter, Shaina N., Magee, Jeffrey A.
Publicado no Exp Hematol (2017)

Lentiviral and targeted cellular barcoding reveals ongoing clonal dynamics of cell lines in vitro and in vivo

por Porter, Shaina N, Baker, Lee C, Mittelman, David, Porteus, Matthew H
Publicado em 2014

Therapeutic gene editing strategies using CRISPR-Cas9 for the β-hemoglobinopathies

por Papizan, James B., Porter, Shaina N., Sharma, Akshay, Pruett-Miller, Shondra M.
Publicado no J Biomed Res (2021)

Attenuation of Zinc Finger Nuclease Toxicity by Small-Molecule Regulation of Protein Levels

por Pruett-Miller, Shondra M., Reading, David W., Porter, Shaina N., Porteus, Matthew H.
Publicado em 2009

Fetal and neonatal hematopoietic progenitors are functionally and transcriptionally resistant to Flt3-ITD mutations

por Porter, Shaina N, Cluster, Andrew S, Yang, Wei, Busken, Kelsey A, Patel, Riddhi M, Ryoo, Jiyeon, Magee, Jeffrey A
Publicado no eLife (2016)

Reproducibility of Indel Formation Rates by Comparing GuideRNA Format and Delivery Method

por Delventhal, Kym, Miller, Brandon, Pruett-Miller, Shondra M., Modarai, Shirin, Porter, Shaina N., Regan, Maureen R., Sergison, Elizabeth
Publicado no J Biomol Tech (2019)

Pten Cell Autonomously Modulates the Hematopoietic Stem Cell Response to Inflammatory Cytokines

por Porter, Shaina N., Cluster, Andrew S., Signer, Robert A.J., Voigtmann, Jenna, Monlish, Darlene A., Schuettpelz, Laura G., Magee, Jeffrey A.
Publicado no Stem Cell Reports (2016)

The Zα2 domain of ZBP1 is a molecular switch regulating influenza-induced PANoptosis and perinatal lethality during development

por Kesavardhana, Sannula, Malireddi, R. K. Subbarao, Burton, Amanda R., Porter, Shaina N., Vogel, Peter, Pruett-Miller, Shondra M., Kanneganti, Thirumala-Devi
Publicado no J Biol Chem (2020)

The efficiency of murine MLL-ENL–driven leukemia initiation changes with age and peaks during neonatal development

por Okeyo-Owuor, Theresa, Li, Yanan, Patel, Riddhi M., Yang, Wei, Casey, Emily B., Cluster, Andrew S., Porter, Shaina N., Bryder, David, Magee, Jeffrey A.
Publicado no Blood Adv (2019)

Single cell analysis of neonatal HSC ontogeny reveals gradual and uncoordinated transcriptional reprogramming that begins before birth

por Li, Yanan, Kong, Wenjun, Yang, Wei, Patel, Riddhi M., Casey, Emily B., Okeyo-Owuor, Theresa, White, J. Michael, Porter, Shaina N., Morris, Samantha A., Magee, Jeffrey A.
Publicado no Cell Stem Cell (2020)

Antitumor effects of CAR T cells redirected to the EDB splice variant of fibronectin

por Wagner, Jessica, Wickman, Elizabeth, Shaw, Timothy I., Anido, Alejandro Allo, Langfitt, Deanna, Zhang, Jinghui, Porter, Shaina N., Pruett-Miller, Shondra M., Tillman, Heather, Krenciute, Giedre, Gottschalk, Stephen
Publicado no Cancer Immunol Res (2020)

Integrative network analysis reveals USP7 haploinsufficiency inhibits E-protein activity in pediatric T-lineage acute lymphoblastic leukemia (T-ALL)

por Shaw, Timothy I., Dong, Li, Tian, Liqing, Qian, Chenxi, Liu, Yu, Ju, Bensheng, High, Anthony, Kavdia, Kanisha, Pagala, Vishwajeeth R., Shaner, Bridget, Pei, Deqing, Easton, John, Janke, Laura J., Porter, Shaina N., Ma, Xiaotu, Cheng, Cheng, Pruett-Miller, Shondra M., Choi, John, Yu, Jiyang, Peng, Junmin, Gu, Wei, Look, A. Thomas, Downing, James R., Zhang, Jinghui
Publicado no Sci Rep (2021)

Genome editing of HBG1 and HBG2 to induce fetal hemoglobin

por Métais, Jean-Yves, Doerfler, Phillip A., Mayuranathan, Thiyagaraj, Bauer, Daniel E., Fowler, Stephanie C., Hsieh, Matthew M., Katta, Varun, Keriwala, Sagar, Lazzarotto, Cicera R., Luk, Kevin, Neel, Michael D., Perry, S. Scott, Peters, Samuel T., Porter, Shaina N., Ryu, Byoung Y., Sharma, Akshay, Shea, Devlin, Tisdale, John F., Uchida, Naoya, Wolfe, Scot A., Woodard, Kaitly J., Wu, Yuxuan, Yao, Yu, Zeng, Jing, Pruett-Miller, Shondra, Tsai, Shengdar Q., Weiss, Mitchell J.
Publicado no Blood Adv (2019)

BCL11A enhancer–edited hematopoietic stem cells persist in rhesus monkeys without toxicity

por Demirci, Selami, Zeng, Jing, Wu, Yuxuan, Uchida, Naoya, Shen, Anne H., Pellin, Danilo, Gamer, Jackson, Yapundich, Morgan, Drysdale, Claire, Bonanno, Jasmine, Bonifacino, Aylin C., Krouse, Allen E., Linde, Nathaniel S., Engels, Theresa, Donahue, Robert E., Haro-Mora, Juan J., Leonard, Alexis, Nassehi, Tina, Luk, Kevin, Porter, Shaina N., Lazzarotto, Cicera R., Tsai, Shengdar Q., Weiss, Mitchell J., Pruett-Miller, Shondra M., Wolfe, Scot A., Bauer, Daniel E., Tisdale, John F.
Publicado no J Clin Invest (2020)

Base editing of hematopoietic stem cells rescues sickle cell disease in mice

por Newby, Gregory A., Yen, Jonathan S., Woodard, Kaitly J., Mayuranathan, Thiyagaraj, Lazzarotto, Cicera R., Li, Yichao, Sheppard-Tillman, Heather, Porter, Shaina N., Yao, Yu, Mayberry, Kalin, Everette, Kelcee A., Jang, Yoonjeong, Podracky, Christopher J., Thaman, Elizabeth, Lechauve, Christophe, Sharma, Akshay, Henderson, Jordana M., Richter, Michelle F., Zhao, Kevin T., Miller, Shannon M., Wang, Tina, Koblan, Luke W., McCaffrey, Anton P., Tisdale, John F., Kalfa, Theodosia A., Pruett-Miller, Shondra M., Tsai, Shengdar Q., Weiss, Mitchell J., Liu, David R.
Publicado no Nature (2021)

Germline Genetic IKZF1 Variation and Predisposition to Childhood Acute Lymphoblastic Leukemia

por Churchman, Michelle L., Qian, Maoxiang, te Kronnie, Geertruy, Zhang, Ranran, Yang, Wenjian, Zhang, Hui, Lana, Tobia, Tedrick, Paige, Baskin, Rebekah, Verbist, Katherine, Peters, Jennifer L., Devidas, Meenakshi, Larsen, Eric, Moore, Ian M., Gu, Zhaohui, Qu, Chunxu, Yoshihara, Hiroki, Porter, Shaina N., Pruett-Miller, Shondra M., Wu, Gang, Raetz, Elizabeth, Martin, Paul L., Bowman, W. Paul, Winick, Naomi, Mardis, Elaine, Fulton, Robert, Stanulla, Martin, Evans, William E., Relling, Mary V., Pui, Ching-Hon, Hunger, Stephen P., Loh, Mignon L., Handgretinger, Rupert, Nichols, Kim E., Yang, Jun J., Mullighan, Charles G.
Publicado no Cancer Cell (2018)