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PRKCH regulates hematopoietic stem cell function and predicts poor prognosis in acute myeloid leukemia

Acute myeloid leukemia (AML) cells often co-opt normal hematopoietic stem cell (HSC) programs to drive neoplastic proliferation, and HSC-related gene expression signatures have been identified as biomarkers for poor prognosis in AML patients. We sought to identify new regulators of HSCs and AML cell...

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Detalhes bibliográficos
Publicado no:Exp Hematol
Main Authors: Porter, Shaina N., Magee, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731097/
https://ncbi.nlm.nih.gov/pubmed/28596089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2017.05.006
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