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PRKCH regulates hematopoietic stem cell function and predicts poor prognosis in acute myeloid leukemia
Acute myeloid leukemia (AML) cells often co-opt normal hematopoietic stem cell (HSC) programs to drive neoplastic proliferation, and HSC-related gene expression signatures have been identified as biomarkers for poor prognosis in AML patients. We sought to identify new regulators of HSCs and AML cell...
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| Vydáno v: | Exp Hematol |
|---|---|
| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6731097/ https://ncbi.nlm.nih.gov/pubmed/28596089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2017.05.006 |
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