Reduced hematopoietic stem cell frequency predicts outcome in acute myeloid leukemia

In patients with acute myeloid leukemia and low percentages of aldehyde-dehydrogenase-positive cells, non-leukemic hematopoietic stem cells can be separated from leukemic cells. By relating hematopoietic stem cell frequencies to outcome we detected poor overall- and disease-free survival of patients...

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Udgivet i:Haematologica
Main Authors: Wang, Wenwen, Stiehl, Thomas, Raffel, Simon, Hoang, Van T., Hoffmann, Isabel, Poisa-Beiro, Laura, Saeed, Borhan R., Blume, Rachel, Manta, Linda, Eckstein, Volker, Bochtler, Tilmann, Wuchter, Patrick, Essers, Marieke, Jauch, Anna, Trumpp, Andreas, Marciniak-Czochra, Anna, Ho, Anthony D., Lutz, Christoph
Format: Artigo
Sprog:Inglês
Udgivet: Ferrata Storti Foundation 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685219/
https://ncbi.nlm.nih.gov/pubmed/28550184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2016.163584
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