Contribution of Liver Nonparenchymal Cells to Hepatic Fibrosis: Interactions with the Local Microenvironment

Por Fausther, Michel, Pritchard, Michele T., Popov, Yury V., Bridle, Kim
Publicado no Biomed Res Int (2017)

Role of the receptor for advanced glycation end products in hepatic fibrosis

Por Lohwasser, Christina, Neureiter, Daniel, Popov, Yury, Bauer, Michael, Schuppan, Detlef
Publicado em 2009

Human T cell microparticles circulate in blood of hepatitis patients and induce fibrolytic activation of hepatic stellate cells

Por Kornek, Miroslaw, Popov, Yury, Libermann, Towia A., Afdhal, Nezam H., Schuppan, Detlef
Publicado em 2010

Tumor Necrosis Factor α-Converting Enzyme Inhibition Reverses Hepatic Steatosis and Improves Insulin Sensitivity Markers and Surgical Outcome in Mice

Por de Meijer, Vincent E., Le, Hau D., Meisel, Jonathan A., Sharma, Anisha K., Popov, Yury, Puder, Mark
Publicado em 2011

Specific hepatic delivery of procollagen α1(I) siRNA in lipid-like nanoparticles resolves liver fibrosis

Por Calvente, Carolina Jiménez, Sehgal, Alfica, Popov, Yury, Kim, Yong Ook, Zevallos, Victor, Sahin, Ugur, Diken, Mustafa, Schuppan, Detlef
Publicado no Hepatology (2015)

Gliadin-primed CD4+CD45RBlowCD25− T cells drive gluten-dependent small intestinal damage after adoptive transfer into lymphopenic mice

Por Freitag, Tobias L., Rietdijk, Svend, Junker, Yvonne, Popov, Yury, Bhan, Atul K., Kelly, Ciaran P., Terhorst, Cox, Schuppan, Detlef
Publicado em 2009

Macrophage-mediated phagocytosis of apoptotic cholangiocytes contributes to reversal of experimental biliary fibrosis

Por Popov, Yury, Sverdlov, Deanna Y., Bhaskar, K. Ramakrishnan, Sharma, Anisha K., Millonig, Gunda, Patsenker, Eleonora, Krahenbuhl, Stephan, Krahenbuhl, Lukas, Schuppan, Detlef
Publicado em 2010

Broad-Spectrum Matrix Metalloproteinase Inhibition Curbs Inflammation and Liver Injury but Aggravates Experimental Liver Fibrosis in Mice

Por de Meijer, Vincent E., Sverdlov, Deanna Y., Popov, Yury, Le, Hau D., Meisel, Jonathan A., Nosé, Vânia, Schuppan, Detlef, Puder, Mark
Publicado em 2010

CFTR dysfunction predisposes to fibrotic liver disease in a murine model

Por Martin, Camilia R., Zaman, Munir M., Ketwaroo, Gyanprakash A., Bhutta, Abdul Q., Coronel, Emmanuel, Popov, Yury, Schuppan, Detlef, Freedman, Steven D.
Publicado em 2012

Failure of Fibrotic Liver Regeneration in Mice Is Linked to a Severe Fibrogenic Response Driven by Hepatic Progenitor Cell Activation

Por Kuramitsu, Kaori, Sverdlov, Deanna Y., Liu, Susan B., Csizmadia, Eva, Burkly, Linda, Schuppan, Detlef, Hanto, Douglas W., Otterbein, Leo E., Popov, Yury
Publicado em 2013

Hydroxyproline-containing collagen analogs trigger the release and activation of collagen-sequestered proMMP-2 by competition with prodomain-derived peptide P(33-42)

Por Ruehl, Martin, Muche, Marion, Freise, Christian, Erben, Ulrike, Neumann, Ulf, Schuppan, Detlef, Popov, Yury, Dieterich, Walburga, Zeitz, Martin, Farndale, Richard W, Somasundaram, Rajan
Publicado em 2011

Tissue Transglutaminase Does Not Affect Fibrotic Matrix Stability or Regression of Liver Fibrosis in Mice

Por Popov, Yury, Sverdlov, Deanna Y., Sharma, Anisha K., Bhaskar, K. Ramakrishnan, Li, Shaoyong, Freitag, Tobias L., Lee, James, Dieterich, Walburga, Melino, Gerry, Schuppan, Detlef
Publicado em 2011

Hepatitis C Virus-Specific T cell-Derived Transforming Growth Factor beta is Associated with Slow Hepatic Fibrogenesis

Por Li, Shaoyong, Vriend, Lianne E.M., Nasser, Imad A., Popov, Yury, Afdhal, Nezam H., Koziel, Margaret J., Schuppan, Detlef, Exley, Mark A., Alatrakchi, Nadia
Publicado em 2012

Vascular Endothelial Growth Factor Promotes Fibrosis Resolution and Repair in Mice

Por Yang, Liu, Kwon, Junghee, Popov, Yury, Gajdos, Gabriella B., Ordog, Tamas, Brekken, Rolf A., Mukhopadhyay, Debabrata, Schuppan, Detlef, Bi, Yan, Simonetto, Douglas, Shah, Vijay H.
Publicado em 2014

Fibroblast Growth Factor 21 Limits Lipotoxicity by Promoting Hepatic Fatty Acid Activation in Mice on Methionine and Choline-deficient Diets

Por Fisher, ffolliott M., Chui, Patricia C., Nasser, Imad A., Popov, Yury, Cunniff, Jeremy C., Lundasen, Thomas, Kharitonenkov, Alexei, Schuppan, Detlef, Flier, Jeffrey S., Maratos-Flier, Eleftheria
Publicado no Gastroenterology (2014)

Anti-melanin-concentrating hormone treatment attenuates chronic experimental colitis and fibrosis

Por Ziogas, Dimitrios C., Gras-Miralles, Beatriz, Mustafa, Sarah, Geiger, Brenda M., Najarian, Robert M., Nagel, Jutta M., Flier, Sarah N., Popov, Yury, Tseng, Yu-Hua, Kokkotou, Efi
Publicado em 2013

Integrin αvβ6 Critically Regulates Hepatic Progenitor Cell Function and Promotes Ductular Reaction, Fibrosis, and Tumorigenesis

Por Peng, Zhen-Wei, Ikenaga, Naoki, Liu, Susan B., Sverdlov, Deanna Y., Vaid, Kahini A., Dixit, Richa, Weinreb, Paul H., Violette, Shelia, Sheppard, Dean, Schuppan, Detlef, Popov, Yury
Publicado no Hepatology (2015)

Regulation of dipeptidyl peptidase 8 and 9 expression in activated lymphocytes and injured liver

Por Chowdhury, Sumaiya, Chen, Yiqian, Yao, Tsun-Wen, Ajami, Katerina, Wang, Xin M, Popov, Yury, Schuppan, Detlef, Bertolino, Patrick, McCaughan, Geoffrey W, Yu, Denise MT, Gorrell, Mark D
Publicado em 2013

Mass-encoded synthetic biomarkers for multiplexed urinary monitoring of disease

Por Kwong, Gabriel A., von Maltzahn, Geoffrey, Murugappan, Gayathree, Abudayyeh, Omar, Mo, Steven, Papayannopoulos, Ioannis A., Sverdlov, Deanna Y., Liu, Susan B., Warren, Andrew D., Popov, Yury, Schuppan, Detlef, Bhatia, Sangeeta N.
Publicado em 2012

MACROPHAGE RECRUITMENT BY FIBROCYSTIN-DEFECTIVE BILIARY EPITHELIAL CELLS PROMOTES PORTAL FIBROSIS IN CONGENITAL HEPATIC FIBROSIS

Por Locatelli, Luigi, Cadamuro, Massimiliano, Spirli, Carlo, Fiorotto, Romina, Lecchi, Silvia, Morell, Carola Maria, Popov, Yury, Scirpo, Roberto, De Matteis, Maria, Amenduni, Mariangela, Pietrobattista, Andrea, Torre, Giuliano, Schuppan, Detlef, Fabris, Luca, Strazzabosco, Mario
Publicado no Hepatology (2016)