Tumor Necrosis Factor α-Converting Enzyme Inhibition Reverses Hepatic Steatosis and Improves Insulin Sensitivity Markers and Surgical Outcome in Mice

BACKGROUND: Hepatic steatosis is an established risk factor for complications following major hepatic resection. Pharmacological options to reverse steatosis prior to surgery, however, are lacking. We hypothesized that treatment with the pharmacologic tumor necrosis factor-α converting enzyme (TACE)...

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Detalhes bibliográficos
Main Authors: de Meijer, Vincent E., Le, Hau D., Meisel, Jonathan A., Sharma, Anisha K., Popov, Yury, Puder, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3181348/
https://ncbi.nlm.nih.gov/pubmed/21980496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025587
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