Macrophage-mediated phagocytosis of apoptotic cholangiocytes contributes to reversal of experimental biliary fibrosis

Studies have suggested the reversibility of liver fibrosis, but the mechanisms of fibrosis reversal are poorly understood. We investigated the possible functional link between apoptosis, macrophages, and matrix turnover in rat liver during reversal of fibrosis secondary to bile duct ligation (BDL)....

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Detalhes bibliográficos
Main Authors: Popov, Yury, Sverdlov, Deanna Y., Bhaskar, K. Ramakrishnan, Sharma, Anisha K., Millonig, Gunda, Patsenker, Eleonora, Krahenbuhl, Stephan, Krahenbuhl, Lukas, Schuppan, Detlef
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Liver and Biliary Tract
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838516/
https://ncbi.nlm.nih.gov/pubmed/20056896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00394.2009
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