Suppression of the HPA axis during extrahepatic biliary obstruction induces cholangiocyte proliferation in the rat

Cholestatic patients often present with clinical features suggestive of adrenal insufficiency. In the bile duct-ligated (BDL) model of cholestasis, the hypothalamic-pituitary-adrenal (HPA) axis is suppressed. The consequences of this suppression on cholangiocyte proliferation are unknown. We evaluat...

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Detalhes bibliográficos
Main Authors: Quinn, Matthew, Ueno, Yoshiyuki, Pae, Hae Yong, Huang, Li, Frampton, Gabriel, Galindo, Cheryl, Francis, Heather, Horvat, Darijana, McMillin, Matthew, DeMorrow, Sharon
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Liver and Biliary Tract
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345968/
https://ncbi.nlm.nih.gov/pubmed/21979757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00205.2011
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