Interleukin-6-driven progranulin expression increases cholangiocarcinoma growth by an Akt-dependent mechanism

BACKGROUND AND OBJECTIVES: Cholangiocarcinoma is a devastating cancer of biliary origin with limited treatment options. The growth factor, progranulin, is overexpressed in a number of tumours. The study aims were to assess the expression of progranulin in cholangiocarcinoma and to determine its effe...

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Publicat a:Gut
Autors principals: Frampton, Gabriel, Invernizzi, Pietro, Bernuzzi, Francesca, Pae, Hae Yong, Quinn, Matthew, Horvat, Darijana, Galindo, Cheryl, Huang, Li, McMillin, Matthew, Cooper, Brandon, Rimassa, Lorenza, DeMorrow, Sharon
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498955/
https://ncbi.nlm.nih.gov/pubmed/22068162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2011-300643
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