MACROPHAGE RECRUITMENT BY FIBROCYSTIN-DEFECTIVE BILIARY EPITHELIAL CELLS PROMOTES PORTAL FIBROSIS IN CONGENITAL HEPATIC FIBROSIS

Congenital Hepatic Fibrosis (CHF) is a disease of the biliary epithelium characterized by bile duct changes resembling ductal plate malformations and by progressive peribiliary fibrosis, in the absence of overt necroinflammation. Progressive liver fibrosis leads to portal hypertension and liver fail...

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Vydáno v:Hepatology
Hlavní autoři: Locatelli, Luigi, Cadamuro, Massimiliano, Spirli, Carlo, Fiorotto, Romina, Lecchi, Silvia, Morell, Carola Maria, Popov, Yury, Scirpo, Roberto, De Matteis, Maria, Amenduni, Mariangela, Pietrobattista, Andrea, Torre, Giuliano, Schuppan, Detlef, Fabris, Luca, Strazzabosco, Mario
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764460/
https://ncbi.nlm.nih.gov/pubmed/26645994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28382
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