Loss of Dictyostelium HSPC300 causes a scar-like phenotype and loss of SCAR protein

Tekijä Pollitt, Alice Y, Insall, Robert H
Julkaistu 2009

WASP and SCAR/WAVE proteins: the drivers of actin assembly

Tekijä Pollitt, Alice Y., Insall, Robert H.
Julkaistu 2009

Platelet Adhesion to Podoplanin Under Flow is Mediated by the Receptor CLEC-2 and Stabilised by Src/Syk-Dependent Platelet Signalling

Tekijä Navarro-Núñez, Leyre, Pollitt, Alice Y., Lowe, Kate, Latif, Arusa, Nash, Gerard B., Watson, Steve P.
Julkaisussa Thromb Haemost (2015)

Pseudopod growth and evolution during cell movement is controlled through SCAR/WAVE dephosphorylation

Tekijä Ura, Seiji, Pollitt, Alice Y., Veltman, Douwe M., Morrice, Nicholas A., Machesky, Laura M., Insall, Robert H.
Julkaisussa Curr Biol (2012)

CLEC-2 is not required for platelet aggregation at arteriolar shear

Tekijä Hughes, Craig E., Navarro-Núñez, Leyre, Finney, Brenda A., Mourão-Sá, Diego, Pollitt, Alice Y., Watson, Steve P.
Julkaisussa J Thromb Haemost (2010)

A novel interaction between FlnA and Syk regulates platelet ITAM-mediated receptor signaling and function

Tekijä Falet, Hervé, Pollitt, Alice Y., Begonja, Antonija Jurak, Weber, Sarah E., Duerschmied, Daniel, Wagner, Denisa D., Watson, Steve P., Hartwig, John H.
Julkaistu 2010

Syk-dependent Phosphorylation of CLEC-2: A NOVEL MECHANISM OF HEM-IMMUNORECEPTOR TYROSINE-BASED ACTIVATION MOTIF SIGNALING

Tekijä Séverin, Sonia, Pollitt, Alice Y., Navarro-Nuñez, Leyre, Nash, Craig A., Mourão-Sá, Diego, Eble, Johannes A., Senis, Yotis A., Watson, Steve P.
Julkaistu 2011

CLEC-2 activates Syk through dimerisation

Tekijä Hughes, Craig E., Pollitt, Alice Y., Mori, Jun, Eble, Johannes A., Tomlinson, Michael G., Hartwig, John H., O’Callaghan, Christopher A., Fütterer, Klaus, Watson, Steve P.
Julkaisussa Blood (2010)

Super-Resolution Fluorescence Microscopy Reveals Clustering Behaviour of Chlamydia pneumoniae’s Major Outer Membrane Protein

Tekijä Danson, Amy E., McStea, Alex, Wang, Lin, Pollitt, Alice Y., Martin-Fernandez, Marisa L., Moraes, Isabel, Walsh, Martin A., MacIntyre, Sheila, Watson, Kimberly A.
Julkaisussa Biology (Basel) (2020)

Renal cells activate the platelet receptor CLEC-2 through podoplanin

Tekijä Christou, Charita M., Pearce, Andrew C., Watson, Aleksandra A., Mistry, Anita R., Pollitt, Alice Y., Fenton-May, Angharad E., Johnson, Louise A., Jackson, David G., Watson, Steve P., O'Callaghan, Chris A.
Julkaistu 2008

CLEC-2 expression is maintained on activated platelets and on platelet microparticles

Tekijä Gitz, Eelo, Pollitt, Alice Y., Gitz-Francois, Jerney J., Alshehri, Osama, Mori, Jun, Montague, Samantha, Nash, Gerard B., Douglas, Michael R., Gardiner, Elizabeth E., Andrews, Robert K., Buckley, Christopher D., Harrison, Paul, Watson, Steve P.
Julkaistu 2014

Platelet actin nodules are podosome-like structures dependent on Wiskott–Aldrich syndrome protein and ARP2/3 complex

Tekijä Poulter, Natalie S., Pollitt, Alice Y., Davies, Amy, Malinova, Dessislava, Nash, Gerard B., Hannon, Mike J., Pikramenou, Zoe, Rappoport, Joshua Z., Hartwig, John H., Owen, Dylan M., Thrasher, Adrian J., Watson, Stephen P., Thomas, Steven G.
Julkaisussa Nat Commun (2015)

Syk and Src Family Kinases Regulate C-type Lectin Receptor 2 (CLEC-2)-mediated Clustering of Podoplanin and Platelet Adhesion to Lymphatic Endothelial Cells

Tekijä Pollitt, Alice Y., Poulter, Natalie S., Gitz, Eelo, Navarro-Nuñez, Leyre, Wang, Ying-Jie, Hughes, Craig E., Thomas, Steven G., Nieswandt, Bernhard, Douglas, Michael R., Owen, Dylan M., Jackson, David G., Dustin, Michael L., Watson, Steve P.
Julkaisussa J Biol Chem (2014)

Interspecies differences in protein expression do not impact the spatiotemporal regulation of glycoprotein VI mediated activation

Tekijä Dunster, Joanne L., Unsworth, Amanda J., Bye, Alexander P., Haining, Elizabeth J., Sowa, Marcin A., Di, Ying, Sage, Tanya, Pallini, Chiara, Pike, Jeremy A., Hardy, Alexander T., Nieswandt, Bernhard, García, Ángel, Watson, Steve P., Poulter, Natalie S., Gibbins, Jonathan M., Pollitt, Alice Y.
Julkaisussa J Thromb Haemost (2019)

Phosphorothioate backbone modifications of nucleotide-based drugs are potent platelet activators

Tekijä Flierl, Ulrike, Nero, Tracy L., Lim, Bock, Arthur, Jane F., Yao, Yu, Jung, Stephanie M., Gitz, Eelo, Pollitt, Alice Y., Zaldivia, Maria T.K., Jandrot-Perrus, Martine, Schäfer, Andreas, Nieswandt, Bernhard, Andrews, Robert K., Parker, Michael W., Gardiner, Elizabeth E., Peter, Karlheinz
Julkaisussa J Exp Med (2015)

Inhibition of Btk by Btk-specific concentrations of ibrutinib and acalabrutinib delays but does not block platelet aggregation mediated by glycoprotein VI

Tekijä Nicolson, Phillip L.R., Hughes, Craig E., Watson, Stephanie, Nock, Sophie H., Hardy, Alexander T., Watson, Callum N., Montague, Samantha J., Clifford, Hayley, Huissoon, Aarnoud P., Malcor, Jean-Daniel, Thomas, Mark R., Pollitt, Alice Y., Tomlinson, Michael G., Pratt, Guy, Watson, Steve P.
Julkaisussa Haematologica (2018)

CLEC-2 and Syk in the megakaryocytic/platelet lineage are essential for development

Tekijä Finney, Brenda A., Schweighoffer, Edina, Navarro-Núñez, Leyre, Bénézech, Cecile, Barone, Francesca, Hughes, Craig E., Langan, Stacey A., Lowe, Kate L., Pollitt, Alice Y., Mourao-Sa, Diego, Sheardown, Steve, Nash, Gerard B., Smithers, Nicholas, Reis e Sousa, Caetano, Tybulewicz, Victor L. J., Watson, Steve P.
Julkaistu 2012

Low-dose Btk inhibitors selectively block platelet activation by CLEC-2

Tekijä Nicolson, Phillip L.R., Nock, Sophie H., Hinds, Joshua, Garcia-Quintanilla, Lourdes, Smith, Christopher W., Campos, Joana, Brill, Alexander, Pike, Jeremy A., Khan, Abdullah O., Poulter, Natalie S., Kavanagh, Deidre M., Watson, Stephanie, Watson, Callum N., Clifford, Hayley, Huissoon, Aarnoud P., Pollitt, Alice Y., Eble, Johannes A., Pratt, Guy, Watson, Steve P., Hughes, Craig E.
Julkaisussa Haematologica (2020)