Loss of Dictyostelium HSPC300 causes a scar-like phenotype and loss of SCAR protein

Por Pollitt, Alice Y, Insall, Robert H
Publicado em 2009

WASP and SCAR/WAVE proteins: the drivers of actin assembly

Por Pollitt, Alice Y., Insall, Robert H.
Publicado em 2009

Platelet Adhesion to Podoplanin Under Flow is Mediated by the Receptor CLEC-2 and Stabilised by Src/Syk-Dependent Platelet Signalling

Por Navarro-Núñez, Leyre, Pollitt, Alice Y., Lowe, Kate, Latif, Arusa, Nash, Gerard B., Watson, Steve P.
Publicado no Thromb Haemost (2015)

Pseudopod growth and evolution during cell movement is controlled through SCAR/WAVE dephosphorylation

Por Ura, Seiji, Pollitt, Alice Y., Veltman, Douwe M., Morrice, Nicholas A., Machesky, Laura M., Insall, Robert H.
Publicado no Curr Biol (2012)

CLEC-2 is not required for platelet aggregation at arteriolar shear

Por Hughes, Craig E., Navarro-Núñez, Leyre, Finney, Brenda A., Mourão-Sá, Diego, Pollitt, Alice Y., Watson, Steve P.
Publicado no J Thromb Haemost (2010)

A novel interaction between FlnA and Syk regulates platelet ITAM-mediated receptor signaling and function

Por Falet, Hervé, Pollitt, Alice Y., Begonja, Antonija Jurak, Weber, Sarah E., Duerschmied, Daniel, Wagner, Denisa D., Watson, Steve P., Hartwig, John H.
Publicado em 2010

Syk-dependent Phosphorylation of CLEC-2: A NOVEL MECHANISM OF HEM-IMMUNORECEPTOR TYROSINE-BASED ACTIVATION MOTIF SIGNALING

Por Séverin, Sonia, Pollitt, Alice Y., Navarro-Nuñez, Leyre, Nash, Craig A., Mourão-Sá, Diego, Eble, Johannes A., Senis, Yotis A., Watson, Steve P.
Publicado em 2011

CLEC-2 activates Syk through dimerisation

Por Hughes, Craig E., Pollitt, Alice Y., Mori, Jun, Eble, Johannes A., Tomlinson, Michael G., Hartwig, John H., O’Callaghan, Christopher A., Fütterer, Klaus, Watson, Steve P.
Publicado no Blood (2010)

Super-Resolution Fluorescence Microscopy Reveals Clustering Behaviour of Chlamydia pneumoniae’s Major Outer Membrane Protein

Por Danson, Amy E., McStea, Alex, Wang, Lin, Pollitt, Alice Y., Martin-Fernandez, Marisa L., Moraes, Isabel, Walsh, Martin A., MacIntyre, Sheila, Watson, Kimberly A.
Publicado no Biology (Basel) (2020)

Renal cells activate the platelet receptor CLEC-2 through podoplanin

Por Christou, Charita M., Pearce, Andrew C., Watson, Aleksandra A., Mistry, Anita R., Pollitt, Alice Y., Fenton-May, Angharad E., Johnson, Louise A., Jackson, David G., Watson, Steve P., O'Callaghan, Chris A.
Publicado em 2008

CLEC-2 expression is maintained on activated platelets and on platelet microparticles

Por Gitz, Eelo, Pollitt, Alice Y., Gitz-Francois, Jerney J., Alshehri, Osama, Mori, Jun, Montague, Samantha, Nash, Gerard B., Douglas, Michael R., Gardiner, Elizabeth E., Andrews, Robert K., Buckley, Christopher D., Harrison, Paul, Watson, Steve P.
Publicado em 2014

Platelet actin nodules are podosome-like structures dependent on Wiskott–Aldrich syndrome protein and ARP2/3 complex

Por Poulter, Natalie S., Pollitt, Alice Y., Davies, Amy, Malinova, Dessislava, Nash, Gerard B., Hannon, Mike J., Pikramenou, Zoe, Rappoport, Joshua Z., Hartwig, John H., Owen, Dylan M., Thrasher, Adrian J., Watson, Stephen P., Thomas, Steven G.
Publicado no Nat Commun (2015)

Syk and Src Family Kinases Regulate C-type Lectin Receptor 2 (CLEC-2)-mediated Clustering of Podoplanin and Platelet Adhesion to Lymphatic Endothelial Cells

Por Pollitt, Alice Y., Poulter, Natalie S., Gitz, Eelo, Navarro-Nuñez, Leyre, Wang, Ying-Jie, Hughes, Craig E., Thomas, Steven G., Nieswandt, Bernhard, Douglas, Michael R., Owen, Dylan M., Jackson, David G., Dustin, Michael L., Watson, Steve P.
Publicado no J Biol Chem (2014)

Interspecies differences in protein expression do not impact the spatiotemporal regulation of glycoprotein VI mediated activation

Por Dunster, Joanne L., Unsworth, Amanda J., Bye, Alexander P., Haining, Elizabeth J., Sowa, Marcin A., Di, Ying, Sage, Tanya, Pallini, Chiara, Pike, Jeremy A., Hardy, Alexander T., Nieswandt, Bernhard, García, Ángel, Watson, Steve P., Poulter, Natalie S., Gibbins, Jonathan M., Pollitt, Alice Y.
Publicado no J Thromb Haemost (2019)

Phosphorothioate backbone modifications of nucleotide-based drugs are potent platelet activators

Por Flierl, Ulrike, Nero, Tracy L., Lim, Bock, Arthur, Jane F., Yao, Yu, Jung, Stephanie M., Gitz, Eelo, Pollitt, Alice Y., Zaldivia, Maria T.K., Jandrot-Perrus, Martine, Schäfer, Andreas, Nieswandt, Bernhard, Andrews, Robert K., Parker, Michael W., Gardiner, Elizabeth E., Peter, Karlheinz
Publicado no J Exp Med (2015)

Inhibition of Btk by Btk-specific concentrations of ibrutinib and acalabrutinib delays but does not block platelet aggregation mediated by glycoprotein VI

Por Nicolson, Phillip L.R., Hughes, Craig E., Watson, Stephanie, Nock, Sophie H., Hardy, Alexander T., Watson, Callum N., Montague, Samantha J., Clifford, Hayley, Huissoon, Aarnoud P., Malcor, Jean-Daniel, Thomas, Mark R., Pollitt, Alice Y., Tomlinson, Michael G., Pratt, Guy, Watson, Steve P.
Publicado no Haematologica (2018)

CLEC-2 and Syk in the megakaryocytic/platelet lineage are essential for development

Por Finney, Brenda A., Schweighoffer, Edina, Navarro-Núñez, Leyre, Bénézech, Cecile, Barone, Francesca, Hughes, Craig E., Langan, Stacey A., Lowe, Kate L., Pollitt, Alice Y., Mourao-Sa, Diego, Sheardown, Steve, Nash, Gerard B., Smithers, Nicholas, Reis e Sousa, Caetano, Tybulewicz, Victor L. J., Watson, Steve P.
Publicado em 2012

Low-dose Btk inhibitors selectively block platelet activation by CLEC-2

Por Nicolson, Phillip L.R., Nock, Sophie H., Hinds, Joshua, Garcia-Quintanilla, Lourdes, Smith, Christopher W., Campos, Joana, Brill, Alexander, Pike, Jeremy A., Khan, Abdullah O., Poulter, Natalie S., Kavanagh, Deidre M., Watson, Stephanie, Watson, Callum N., Clifford, Hayley, Huissoon, Aarnoud P., Pollitt, Alice Y., Eble, Johannes A., Pratt, Guy, Watson, Steve P., Hughes, Craig E.
Publicado no Haematologica (2020)