Pseudopod growth and evolution during cell movement is controlled through SCAR/WAVE dephosphorylation

BACKGROUND: SCAR/WAVE is a principal regulator of pseudopod growth in crawling cells. It exists in a stable pentameric complex, which is regulated at multiple levels that are only beginning to be understood. SCAR/WAVE is phosphorylated at multiple sites, but how this affects its biological activity...

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Udgivet i:Curr Biol
Main Authors: Ura, Seiji, Pollitt, Alice Y., Veltman, Douwe M., Morrice, Nicholas A., Machesky, Laura M., Insall, Robert H.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961229/
https://ncbi.nlm.nih.gov/pubmed/22386315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.02.020
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