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SCAR knockouts in Dictyostelium: WASP assumes SCAR’s position and upstream regulators in pseudopods
Under normal conditions, the Arp2/3 complex activator SCAR/WAVE controls actin polymerization in pseudopods, whereas Wiskott–Aldrich syndrome protein (WASP) assembles actin at clathrin-coated pits. We show that, unexpectedly, Dictyostelium discoideum SCAR knockouts could still spread, migrate, and c...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Rockefeller University Press
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3514037/ https://ncbi.nlm.nih.gov/pubmed/22891261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201205058 |
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