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WASP family proteins and formins compete in pseudopod- and bleb-based migration

Actin pseudopods induced by SCAR/WAVE drive normal migration and chemotaxis in eukaryotic cells. Cells can also migrate using blebs, in which the edge is driven forward by hydrostatic pressure instead of actin. In Dictyostelium discoideum, loss of SCAR is compensated by WASP moving to the leading ed...

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Bibliografske podrobnosti
izdano v:J Cell Biol
Main Authors: Davidson, Andrew J., Amato, Clelia, Thomason, Peter A., Insall, Robert H.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800805/
https://ncbi.nlm.nih.gov/pubmed/29191847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201705160
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