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Pressure sensing through Piezo channels controls whether cells migrate with blebs or pseudopods

Blebs and pseudopods can both power cell migration, with blebs often favored in tissues, where cells encounter increased mechanical resistance. To investigate how migrating cells detect and respond to mechanical forces, we used a “cell squasher” to apply uniaxial pressure to Dictyostelium cells chem...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Srivastava, Nishit, Traynor, David, Piel, Matthieu, Kabla, Alexandre J., Kay, Robert R.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007555/
https://ncbi.nlm.nih.gov/pubmed/31964823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1905730117
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