Platelet actin nodules are podosome-like structures dependent on Wiskott–Aldrich syndrome protein and ARP2/3 complex

The actin nodule is a novel F-actin structure present in platelets during early spreading. However, only limited detail is known regarding nodule organization and function. Here we use electron microscopy, SIM and dSTORM super-resolution, and live-cell TIRF microscopy to characterize the structural...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Poulter, Natalie S., Pollitt, Alice Y., Davies, Amy, Malinova, Dessislava, Nash, Gerard B., Hannon, Mike J., Pikramenou, Zoe, Rappoport, Joshua Z., Hartwig, John H., Owen, Dylan M., Thrasher, Adrian J., Watson, Stephen P., Thomas, Steven G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458878/
https://ncbi.nlm.nih.gov/pubmed/26028144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8254
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