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Platelet actin nodules are podosome-like structures dependent on Wiskott–Aldrich syndrome protein and ARP2/3 complex

The actin nodule is a novel F-actin structure present in platelets during early spreading. However, only limited detail is known regarding nodule organization and function. Here we use electron microscopy, SIM and dSTORM super-resolution, and live-cell TIRF microscopy to characterize the structural...

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Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Poulter, Natalie S., Pollitt, Alice Y., Davies, Amy, Malinova, Dessislava, Nash, Gerard B., Hannon, Mike J., Pikramenou, Zoe, Rappoport, Joshua Z., Hartwig, John H., Owen, Dylan M., Thrasher, Adrian J., Watson, Stephen P., Thomas, Steven G.
Format: Artigo
Idioma:Inglês
Publicat: Nature Pub. Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458878/
https://ncbi.nlm.nih.gov/pubmed/26028144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8254
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