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The Wiskott-Aldrich Syndrome: The Actin Cytoskeleton and Immune Cell Function

Wiskott-Aldrich syndrome (WAS) is a rare X-linked recessive primary immunodeficiency characterised by immune dysregulation, microthrombocytopaenia, eczema and lymphoid malignancies. Mutations in the WAS gene can lead to distinct syndrome variations which largely, although not exclusively, depend upo...

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Detalhes bibliográficos
Main Authors: Blundell, Michael P., Worth, Austen, Bouma, Gerben, Thrasher, Adrian J.
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835520/
https://ncbi.nlm.nih.gov/pubmed/21178275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/DMA-2010-0735
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