The Wiskott-Aldrich Syndrome: The Actin Cytoskeleton and Immune Cell Function

Wiskott-Aldrich syndrome (WAS) is a rare X-linked recessive primary immunodeficiency characterised by immune dysregulation, microthrombocytopaenia, eczema and lymphoid malignancies. Mutations in the WAS gene can lead to distinct syndrome variations which largely, although not exclusively, depend upo...

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Bibliographic Details
Main Authors: Blundell, Michael P., Worth, Austen, Bouma, Gerben, Thrasher, Adrian J.
Format: Artigo
Language:Inglês
Published: IOS Press 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835520/
https://ncbi.nlm.nih.gov/pubmed/21178275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/DMA-2010-0735
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