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Wiskott–Aldrich Syndrome: Immunodeficiency resulting from defective cell migration and impaired immunostimulatory activation

Regulation of the actin cytoskeleton is crucial for many aspects of correct and cooperative functioning of immune cells, such as migration, antigen uptake and cell activation. The Wiskott–Aldrich Syndrome protein (WASp) is an important regulator of actin cytoskeletal rearrangements and lack of this...

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Détails bibliographiques
Auteurs principaux: Bouma, Gerben, Burns, Siobhan O., Thrasher, Adrian J.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738782/
https://ncbi.nlm.nih.gov/pubmed/19628299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imbio.2009.06.009
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