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Wiskott–Aldrich Syndrome: Immunodeficiency resulting from defective cell migration and impaired immunostimulatory activation

Regulation of the actin cytoskeleton is crucial for many aspects of correct and cooperative functioning of immune cells, such as migration, antigen uptake and cell activation. The Wiskott–Aldrich Syndrome protein (WASp) is an important regulator of actin cytoskeletal rearrangements and lack of this...

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Detalhes bibliográficos
Main Authors: Bouma, Gerben, Burns, Siobhan O., Thrasher, Adrian J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738782/
https://ncbi.nlm.nih.gov/pubmed/19628299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imbio.2009.06.009
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