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Wiskott-Aldrich syndrome protein deficiency in B cells results in impaired peripheral homeostasis

To more precisely identify the B-cell phenotype in Wiskott-Aldrich syndrome (WAS), we used 3 distinct murine in vivo models to define the cell intrinsic requirements for WAS protein (WASp) in central versus peripheral B-cell development. Whereas WASp is dispensable for early bone marrow B-cell devel...

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Библиографические подробности
Главные авторы: Meyer-Bahlburg, Almut, Becker-Herman, Shirly, Humblet-Baron, Stephanie, Khim, Socheath, Weber, Michele, Bouma, Gerben, Thrasher, Adrian J., Batista, Facundo D., Rawlings, David J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582000/
https://ncbi.nlm.nih.gov/pubmed/18687984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-02-140814
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