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Wiskott-Aldrich syndrome protein is required for regulatory T cell homeostasis
Wiskott-Aldrich syndrome protein (WASp) is essential for optimal T cell activation. Patients with WAS exhibit both immunodeficiency and a marked susceptibility to systemic autoimmunity. We investigated whether alterations in Treg function might explain these paradoxical observations. While WASp-defi...
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| Glavni autori: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Clinical Investigation
2007
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1764857/ https://ncbi.nlm.nih.gov/pubmed/17218989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI29539 |
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