Targeting bioenergetics to enhance cancer chemotherapy: mitochondria SLP into apoptosis

Por Khatri, Shikha, Plas, David R.
Publicado em 2009

ATPS-66 INVESTIGATING S6K1 INHIBITORS FOR TARGETING PTEN-DEFICIENT GLIOBLASTOMA

Por Ennis, Kelli, Feng, Xizhi, Gallo, Catherine, Plas, David
Publicado no Neuro Oncol (2015)

Not all autophagy is equal

Por Czyzyk-Krzeska, Maria F., Meller, Jarek, Plas, David R.
Publicado em 2012

FOXO3a Regulates Glycolysis via Transcriptional Control of Tumor Suppressor TSC1

Por Khatri, Shikha, Yepiskoposyan, Hasmik, Gallo, Catherine A., Tandon, Preeti, Plas, David R.
Publicado em 2010

IKKβ and NFκB transcription govern lymphoma cell survival through AKT-induced plasma membrane trafficking of GLUT1

Por Sommermann, Thomas, O’Neill, Kathleen, Plas, David R., Cahir-McFarland, Ellen
Publicado em 2011

Loss of immunological tolerance in Gimap5-deficient mice is associated with loss of Foxo in CD4(+) T cells

Por Aksoylar, H. Ibrahim, Lampe, Kristin, Barnes, Michael J., Plas, David R., Hoebe, Kasper
Publicado em 2011

Requirement for ribosomal protein S6 kinase 1 to mediate glycolysis and apoptosis resistance induced by Pten deficiency

Por Tandon, Preeti, Gallo, Catherine A., Khatri, Shikha, Barger, Jennifer F., Yepiskoposyan, Hasmik, Plas, David R.
Publicado em 2011

IL-15 Fosters Age-Driven Regulatory T Cell Accrual in the Face of Declining IL-2 Levels

Por Raynor, Jana, Sholl, Allyson, Plas, David R., Bouillet, Philippe, Chougnet, Claire A., Hildeman, David A.
Publicado em 2013

Akt-Directed Glucose Metabolism Can Prevent Bax Conformation Change and Promote Growth Factor-Independent Survival

Por Rathmell, Jeffrey C., Fox, Casey J., Plas, David R., Hammerman, Peter S., Cinalli, Ryan M., Thompson, Craig B.
Publicado em 2003

S6K1 determines the metabolic requirements for BCR-ABL survival

Por Barger, Jennifer F., Gallo, Catherine A., Tandon, Preeti, Liu, Hongqi, Sullivan, Ashley, Grimes, H. Leighton, Plas, David R.
Publicado em 2012

ERK2 mediates metabolic stress response to regulate cell fate

Por Shin, Sejeong, Buel, Gwen R., Wolgamott, Laura, Plas, David R., Asara, John M., Blenis, John, Yoon, Sang-Oh
Publicado no Mol Cell (2015)

Growth Factors Can Influence Cell Growth and Survival through Effects on Glucose Metabolism

Por Vander Heiden, Matthew G., Plas, David R., Rathmell, Jeffrey C., Fox, Casey J., Harris, Marian H., Thompson, Craig B.
Publicado em 2001

A major role for Bim in regulatory T cell homeostasis

Por Chougnet, Claire A., Tripathi, Pulak, Lages, Celine S., Raynor, Jana, Sholl, Allyson, Fink, Pamela, Plas, David R., Hildeman, David A.
Publicado em 2010

Akt-Dependent Glucose Metabolism Promotes Mcl-1 Synthesis to Maintain Cell Survival and Resistance to Bcl-2 Inhibition

Por Coloff, Jonathan L., Macintyre, Andrew N., Nichols, Amanda G., Liu, Tingyu, Gallo, Catherine A., Plas, David R., Rathmell, Jeffrey C.
Publicado em 2011

Identification of a Conserved Anti-Apoptotic Protein That Modulates the Mitochondrial Apoptosis Pathway

Por Zhang, Yu, Johansson, Elisabet, Miller, Marian L., Jänicke, Reiner U., Ferguson, Donald J., Plas, David, Meller, Jarek, Anderson, Marshall W.
Publicado em 2011

Cytokine stimulation of aerobic glycolysis in hematopoietic cells exceeds proliferative demand

Por Bauer, Daniel E., Harris, Marian H., Plas, David R., Lum, Julian J., Hammerman, Peter S., Rathmell, Jeffrey C., Riley, James L., Thompson, Craig B.
Publicado no FASEB J (2004)

S6K1 regulates hematopoietic stem cell self-renewal and leukemia maintenance

Por Ghosh, Joydeep, Kobayashi, Michihiro, Ramdas, Baskar, Chatterjee, Anindya, Ma, Peilin, Mali, Raghuveer Singh, Carlesso, Nadia, Liu, Yan, Plas, David R., Chan, Rebecca J., Kapur, Reuben
Publicado no J Clin Invest (2016)

ERRα regulates the growth of triple-negative breast cancer cells via S6K1-dependent mechanism

Por Berman, Adi Y, Manna, Subrata, Schwartz, Naomi S, Katz, Yardena E, Sun, Yang, Behrmann, Catherine A, Yu, Jane J, Plas, David R, Alayev, Anya, Holz, Marina K
Publicado no Signal Transduct Target Ther (2017)

VHL-regulated miR-204 Suppresses Tumor Growth through Inhibition of LC3B-mediated Autophagy in Renal Clear Cell Carcinoma

Por Mikhaylova, Olga, Stratton, Yiwen, Hall, Daniel, Kellner, Emily, Ehmer, Birgit, Drew, Angela F., Gallo, Catherine A., Plas, David R., Biesiada, Jacek, Meller, Jarek, Czyzyk-Krzeska, Maria F.
Publicado em 2012

Focal adhesion- and IGF1R-dependent survival and migratory pathways mediate tumor resistance to mTORC1/2 inhibition

Por Yoon, Sang-Oh, Shin, Sejeong, Karreth, Florian A., Buel, Gwen R., Jedrychowski, Mark P., Plas, David R., Dedhar, Shoukat, Gygi, Steven P., Roux, Philippe P., Dephoure, Noah, Blenis, John
Publicado no Mol Cell (2017)