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IL-15 Fosters Age-Driven Regulatory T Cell Accrual in the Face of Declining IL-2 Levels
We and others have shown that regulatory T cells (T(reg)) accumulate dramatically with age in both humans and mice. Such T(reg) accrual contributes to age-related immunosenescence as they reduce the response to tumors and parasite infection. While we reported earlier that aged T(reg) have decreased...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Frontiers Media S.A.
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3690359/ https://ncbi.nlm.nih.gov/pubmed/23805138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00161 |
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