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A major role for Bim in regulatory T cell homeostasis

We have previously shown that regulatory T cells (T(reg)) accumulate dramatically in aged animals and negatively impact the ability to control persistent infection. However, the mechanism(s) underlying the age-dependent accrual of T(reg) remain unclear. Here, we show that T(reg) accumulation with ag...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chougnet, Claire A., Tripathi, Pulak, Lages, Celine S., Raynor, Jana, Sholl, Allyson, Fink, Pamela, Plas, David R., Hildeman, David A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066029/
https://ncbi.nlm.nih.gov/pubmed/21098226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001505
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