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IL-6 and ICOS antagonize Bim and promote Treg accrual with age
Regulatory T cells (Treg), a subset of CD4+ T cells, dramatically accumulate with age in humans and mice and contribute to age-related immune suppression. Recently, we showed that a majority of accumulating Treg in aged mice expressed low levels of CD25 and their accrual is associated with declining...
Sparad:
| I publikationen: | J Immunol |
|---|---|
| Huvudupphovsmän: | , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2015
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4506860/ https://ncbi.nlm.nih.gov/pubmed/26109645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500443 |
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