IL-10–producing Tfh cells accumulate with age and link inflammation with age-related immune suppression

Aging results in profound immune dysfunction, resulting in the decline of vaccine responsiveness previously attributed to irreversible defects in the immune system. In addition to increased interleukin-6 (IL-6), we found aged mice exhibit increased systemic IL-10 that requires forkhead box P3–negati...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Sci Adv
Главные авторы: Almanan, Maha, Raynor, Jana, Ogunsulire, Ireti, Malyshkina, Anna, Mukherjee, Shibabrata, Hummel, Sarah A., Ingram, Jennifer T., Saini, Ankur, Xie, Markus M., Alenghat, Theresa, Way, Sing Sing, Deepe, George S., Divanovic, Senad, Singh, Harinder, Miraldi, Emily, Zajac, Allan J., Dent, Alexander L., Hölscher, Christoph, Chougnet, Claire, Hildeman, David A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Association for the Advancement of Science 2020
Предметы:
Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7439492/
https://ncbi.nlm.nih.gov/pubmed/32832688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb0806
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы