Reduced Emergence of Isoniazid Resistance with Concurrent Use of Thioridazine against Acute Murine Tuberculosis

Por Dutta, Noton K., Pinn, Michael L., Karakousis, Petros C.
Publicado em 2014

Sterilizing Activity of Thioridazine in Combination with the First-Line Regimen against Acute Murine Tuberculosis

Por Dutta, Noton K., Pinn, Michael L., Karakousis, Petros C.
Publicado em 2014

Thioridazine lacks bactericidal activity in an animal model of extracellular tuberculosis

Por Dutta, Noton K., Pinn, Michael L., Zhao, Ming, Rudek, Michelle A., Karakousis, Petros C.
Publicado em 2013

Simvastatin increases the in vivo activity of the first-line tuberculosis regimen

Por Skerry, Ciaran, Pinn, Michael L., Bruiners, Natalie, Pine, Richard, Gennaro, Maria L., Karakousis, Petros C.
Publicado em 2014

Vaccination with Recombinant Mycobacterium tuberculosis PknD Attenuates Bacterial Dissemination to the Brain in Guinea Pigs

Por Skerry, Ciaran, Pokkali, Supriya, Pinn, Michael, Be, Nicholas A., Harper, Jamie, Karakousis, Petros C., Jain, Sanjay K.
Publicado em 2013

The potent bactericidal activity of streptomycin in the guinea pig model of tuberculosis ceases due to the presence of persisters

Por Ahmad, Zahoor, Pinn, Michael L., Nuermberger, Eric L., Peloquin, Charles A., Grosset, Jacques H., Karakousis, Petros C.
Publicado em 2010

Experimental Ocular Tuberculosis in Guinea Pigs

Por Rao, Narsing A., Albini, Thomas A., Kumaradas, Mirnalini, Pinn, Michael L., Fraig, Mostafa M., Karakousis, Petros C.
Publicado em 2009

Mycobacterial Protein Tyrosine Phosphatases A and B Inhibitors Augment the Bactericidal Activity of the Standard Anti-tuberculosis Regimen

Por Dutta, Noton K., He, Rongjun, Pinn, Michael L., He, Yantao, Burrows, Francis, Zhang, Zhong-Yin, Karakousis, Petros C.
Publicado no ACS Infect Dis (2015)

Effectiveness of tuberculosis chemotherapy correlates with resistance to Mycobacterium tuberculosis infection in animal models

Por Ahmad, Zahoor, Fraig, Mostafa M., Pinn, Michael L., Tyagi, Sandeep, Nuermberger, Eric L., Grosset, Jacques H., Karakousis, Petros C.
Publicado em 2011

High Systemic Exposure of Pyrazinoic Acid Has Limited Antituberculosis Activity in Murine and Rabbit Models of Tuberculosis

Por Lanoix, Jean-Philippe, Tasneen, Rokeya, O'Brien, Paul, Sarathy, Jansy, Safi, Hassan, Pinn, Michael, Alland, David, Dartois, Véronique, Nuermberger, Eric
Publicado no Antimicrob Agents Chemother (2016)

Statin adjunctive therapy shortens the duration of TB treatment in mice

Por Dutta, Noton K., Bruiners, Natalie, Pinn, Michael L., Zimmerman, Matthew D., Prideaux, Brendan, Dartois, Véronique, Gennaro, Maria L., Karakousis, Petros C.
Publicado no J Antimicrob Chemother (2016)

Comparison of the ‘Denver regimen’ against acute tuberculosis in the mouse and guinea pig

Por Ahmad, Zahoor, Nuermberger, Eric L., Tasneen, Rokeya, Pinn, Michael L., Williams, Kathy N., Peloquin, Charles A., Grosset, Jacques H., Karakousis, Petros C.
Publicado em 2010

Rifapentine Is Not More Active than Rifampin against Chronic Tuberculosis in Guinea Pigs

Por Dutta, Noton K., Illei, Peter B., Peloquin, Charles A., Pinn, Michael L., Mdluli, Khisimuzi E., Nuermberger, Eric L., Grosset, Jacques H., Karakousis, Petros C.
Publicado em 2012

Potent Rifamycin-Sparing Regimen Cures Guinea Pig Tuberculosis as Rapidly as the Standard Regimen

Por Dutta, Noton K., Alsultan, Abdullah, Gniadek, Thomas J., Belchis, Deborah A., Pinn, Michael L., Mdluli, Khisimuzi E., Nuermberger, Eric L., Peloquin, Charles A., Karakousis, Petros C.
Publicado em 2013