Rifapentine Is Not More Active than Rifampin against Chronic Tuberculosis in Guinea Pigs

Rifamycins are key sterilizing drugs in the current treatment of active tuberculosis (TB). Daily dosing of rifapentine (P), a potent rifamycin with high intracellular accumulation, in place of rifampin (R) in the standard antitubercular regimen significantly shortens the duration of treatment needed...

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Detalhes bibliográficos
Main Authors: Dutta, Noton K., Illei, Peter B., Peloquin, Charles A., Pinn, Michael L., Mdluli, Khisimuzi E., Nuermberger, Eric L., Grosset, Jacques H., Karakousis, Petros C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393407/
https://ncbi.nlm.nih.gov/pubmed/22547623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00500-12
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