Comparison of the ‘Denver regimen’ against acute tuberculosis in the mouse and guinea pig

OBJECTIVES: In this study, we sought to compare the sterilizing activity of human-equivalent doses of the ‘Denver regimen’ against acute tuberculosis (TB) infection in the standard mouse model and in the guinea pig. METHODS: Pharmacokinetic studies in guinea pigs were used to establish human-equival...

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Autores principales: Ahmad, Zahoor, Nuermberger, Eric L., Tasneen, Rokeya, Pinn, Michael L., Williams, Kathy N., Peloquin, Charles A., Grosset, Jacques H., Karakousis, Petros C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2010
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837551/
https://ncbi.nlm.nih.gov/pubmed/20123722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkq007
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