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Thioridazine lacks bactericidal activity in an animal model of extracellular tuberculosis

OBJECTIVES: The antipsychotic drug thioridazine is active in the murine model of tuberculosis infection, which is predominantly intracellular in nature. Recent clinical reports suggest that thioridazine may play a role in the treatment of drug-resistant tuberculosis. We studied the tuberculocidal ac...

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Detalhes bibliográficos
Main Authors: Dutta, Noton K., Pinn, Michael L., Zhao, Ming, Rudek, Michelle A., Karakousis, Petros C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654222/
https://ncbi.nlm.nih.gov/pubmed/23463208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkt037
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