Structural insight into the mechanism of substrate specificity and catalytic activity of an HD domain phosphohydrolase: the 5′-deoxyribonucleotidase YfbR from Escherichia coli

Por Zimmerman, Matthew D., Proudfoot, Michael, Yakunin, Alexander, Minor, Wladek
Publicado em 2008

The Impact of Structural Genomics: the First Quindecennial

Por Grabowski, Marek, Niedzialkowska, Ewa, Zimmerman, Matthew D., Minor, Wladek
Publicado no J Struct Funct Genomics (2016)

Benefits of Structural Genomics for Drug Discovery Research

Por Grabowski, Marek, Chruszcz, Maksymilian, Zimmerman, Matthew D., Kirillova, Olga, Minor, Wladek
Publicado em 2009

The future of crystallography in drug discovery

Por Zheng, Heping, Hou, Jing, Zimmerman, Matthew D, Wlodawer, Alexander, Minor, Wladek
Publicado em 2013

‘Hot’ macromolecular crystals

Por Koclega, Katarzyna D., Chruszcz, Maksymilian, Zimmerman, Matthew D., Bujacz, Grzegorz, Minor, Wladek
Publicado em 2009

Crystal structure of a transcriptional regulator TM1030 from Thermotoga maritima solved by an unusual MAD experiment

Por Koclega, Katarzyna D., Chruszcz, Maksymilian, Zimmerman, Matthew D., Cymborowski, Marcin, Evdokimova, Elena, Minor, Wladek
Publicado em 2007

The Quality and Validation of Structures from Structural Genomics

Por Domagalski, Marcin J., Zheng, Heping, Zimmerman, Matthew D., Dauter, Zbigniew, Wlodawer, Alexander, Minor, Wladek
Publicado em 2014

Analysis of solvent content and oligomeric states in protein crystals—does symmetry matter?

Por Chruszcz, Maksymilian, Potrzebowski, Wojciech, Zimmerman, Matthew D., Grabowski, Marek, Zheng, Heping, Lasota, Piotr, Minor, Wladek
Publicado em 2008

Data Management in the Modern Structural Biology and Biomedical Research Environment

Por Zimmerman, Matthew D., Grabowski, Marek, Domagalski, Marcin J., MacLean, Elizabeth M., Chruszcz, Maksymilian, Minor, Wladek
Publicado em 2014

X-ray crystallography over the past decade for novel drug discovery – where are we heading next?

Por Zheng, Heping, Handing, Katarzyna B, Zimmerman, Matthew D, Shabalin, Ivan G, Almo, Steven C, Minor, Wladek
Publicado no Expert Opin Drug Discov (2015)

New surface contacts formed upon reductive lysine methylation: Improving the probability of protein crystallization

Por Sledz, Pawel, Zheng, Heping, Murzyn, Krzysztof, Chruszcz, Maksymilian, Zimmerman, Matthew D, Chordia, Mahendra D, Joachimiak, Andrzej, Minor, Wladek
Publicado em 2010

Structural and immunologic characterization of bovine, horse, and rabbit serum albumins

Por Majorek, Karolina A., Porebski, Przemyslaw J., Dayal, Arjun, Zimmerman, Matthew D., Jablonska, Kamila, Stewart, Alan J., Chruszcz, Maksymilian, Minor, Wladek
Publicado em 2012

Dissecting the Structural Elements for the Activation of β-Ketoacyl-(Acyl Carrier Protein) Reductase from Vibrio cholerae

Por Hou, Jing, Zheng, Heping, Chruszcz, Maksymilian, Zimmerman, Matthew D., Shumilin, Igor A., Osinski, Tomasz, Demas, Matt, Grimshaw, Sarah, Minor, Wladek
Publicado no J Bacteriol (2016)

Crystal structure and molecular modeling study of N-carbamoylsarcosine amidase Ta0454 from Thermoplasma acidophilum

Por Luo, Hai-Bin, Zheng, Heping, Zimmerman, Matthew D., Chruszcz, Maksymilian, Skarina, Tatiana, Egorova, Olga, Savchenko, Alexei, Edwards, Aled M., Minor, Wladek
Publicado em 2009

Statin adjunctive therapy shortens the duration of TB treatment in mice

Por Dutta, Noton K., Bruiners, Natalie, Pinn, Michael L., Zimmerman, Matthew D., Prideaux, Brendan, Dartois, Véronique, Gennaro, Maria L., Karakousis, Petros C.
Publicado no J Antimicrob Chemother (2016)

Function-biased choice of additives for optimization of protein crystallization – the case of the putative thioesterase PA5185 from Pseudomonas aeruginosa PAO1

Por Chruszcz, Maksymilian, Zimmerman, Matthew D., Wang, Shuren, Koclega, Katarzyna D., Zheng, Heping, Evdokimova, Elena, Kudritska, Marina, Cymborowski, Marcin, Savchenko, Alexei, Edwards, Aled, Minor, Wladek
Publicado em 2008

Crystal structures of TM0549 and NE1324—two orthologs of E. coli AHAS isozyme III small regulatory subunit

Por Petkowski, Janusz J., Chruszcz, Maksymilian, Zimmerman, Matthew D., Zheng, Heping, Skarina, Tatiana, Onopriyenko, Olena, Cymborowski, Marcin T., Koclega, Katarzyna D., Savchenko, Alexei, Edwards, Aled, Minor, Wladek
Publicado em 2007

Immune activation of the host cell induces drug tolerance in Mycobacterium tuberculosis both in vitro and in vivo

Por Liu, Yancheng, Tan, Shumin, Huang, Lu, Abramovitch, Robert B., Rohde, Kyle H., Zimmerman, Matthew D., Chen, Chao, Dartois, Véronique, VanderVen, Brian C., Russell, David G.
Publicado no J Exp Med (2016)

The crystal structure of the AF2331 protein from Archaeoglobus fulgidus DSM 4304 forms an unusual interdigitated dimer with a new type of α + β fold

Por Wang, Shuren, Kirillova, Olga, Chruszcz, Maksymilian, Gront, Dominik, Zimmerman, Matthew D, Cymborowski, Marcin T, Shumilin, Igor A, Skarina, Tatiana, Gorodichtchenskaia, Elena, Savchenko, Alexei, Edwards, Aled M, Minor, Wladek
Publicado em 2009

A public database of macromolecular diffraction experiments

Por Grabowski, Marek, Langner, Karol M., Cymborowski, Marcin, Porebski, Przemyslaw J., Sroka, Piotr, Zheng, Heping, Cooper, David R., Zimmerman, Matthew D., Elsliger, Marc-André, Burley, Stephen K., Minor, Wladek
Publicado no Acta Crystallogr D Struct Biol (2016)