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The future of crystallography in drug discovery

INTRODUCTION: X-ray crystallography plays an important role in structure-based drug design (SBDD), and accurate analysis of crystal structures of target macromolecules and macromolecule–ligand complexes is critical at all stages. However, whereas there has been significant progress in improving meth...

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Main Authors: Zheng, Heping, Hou, Jing, Zimmerman, Matthew D, Wlodawer, Alexander, Minor, Wladek
格式: Artigo
語言:Inglês
出版: 2013
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106240/
https://ncbi.nlm.nih.gov/pubmed/24372145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17460441.2014.872623
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