Structural Asymmetry of Phosphodiesterase-9, Potential Protonation of a Glutamic Acid, and Role of the Invariant Glutamine

Por Hou, Jing, Xu, Jie, Liu, Ming, Zhao, Ruizhi, Luo, Hai-Bin, Ke, Hengming
Publicado em 2011

Computational Design of a Time-Dependent Histone Deacetylase 2 Selective Inhibitor

Por Zhou, Jingwei, Li, Min, Chen, Nanhao, Wang, Shenglong, Luo, Hai-Bin, Zhang, Yingkai, Wu, Ruibo
Publicado no ACS Chem Biol (2014)

Six New Tetraprenylated Alkaloids from the South China Sea Gorgonian Echinogorgia pseudossapo

Por Sun, Zhang-Hua, Cai, Ying-Hong, Fan, Cheng-Qi, Tang, Gui-Hua, Luo, Hai-Bin, Yin, Sheng
Publicado em 2014

Discovery of novel PDE9 inhibitors capable of inhibiting Aβ aggregation as potential candidates for the treatment of Alzheimer’s disease

Por Su, Tao, Zhang, Tianhua, Xie, Shishun, Yan, Jun, Wu, Yinuo, Li, Xingshu, Huang, Ling, Luo, Hai-Bin
Publicado no Sci Rep (2016)

Biophysical analysis of the putative acetyltransferase SACOL2570 from methicillin-resistant Staphylococcus aureus

Por Luo, Hai-Bin, Knapik, Aleksandra A., Petkowski, Janusz J., Demas, Matthew, Shumilin, Igor A., Zheng, Heping, Chruszcz, Maksymilian, Minor, Wladek
Publicado em 2013

Crystal structure and molecular modeling study of N-carbamoylsarcosine amidase Ta0454 from Thermoplasma acidophilum

Por Luo, Hai-Bin, Zheng, Heping, Zimmerman, Matthew D., Chruszcz, Maksymilian, Skarina, Tatiana, Egorova, Olga, Savchenko, Alexei, Edwards, Aled M., Minor, Wladek
Publicado em 2009

Discovery of a Phosphodiesterase 9A Inhibitor as a Potential Hypoglycemic Agent

Por Shao, Yong-xian, Huang, Manna, Cui, Wenjun, Feng, Ling-Jun, Wu, Yinuo, Cai, Yinghong, Li, Zhe, Zhu, Xinhai, Liu, Peiqing, Wan, Yiqian, Ke, Hengming, Luo, Hai-Bin
Publicado no J Med Chem (2014)

Structural Asymmetry of Phosphodiesterase-9A and a Unique Pocket for Selective Binding of a Potent Enantiomeric Inhibitor

Por Huang, Manna, Shao, Yongxian, Hou, Jianying, Cui, Wenjun, Liang, Beibei, Huang, Yingchun, Li, Zhe, Wu, Yinuo, Zhu, Xinhai, Liu, Peiqing, Wan, Yiqian, Ke, Hengming, Luo, Hai-Bin
Publicado no Mol Pharmacol (2015)

Structure-based discovery of highly selective phosphodiesterase-9A inhibitors and implications for inhibitor design

Por Meng, Fei, Hou, Jing, Shao, Yong-Xian, Wu, Pei-Ying, Huang, Manna, Zhu, Xinhai, Cai, Yonghong, Li, Zhe, Xu, Jie, Liu, Peiqing, Luo, Hai-Bin, Wan, Yiqian, Ke, Hengming
Publicado em 2012

Ellagic acid, a phenolic compound, exerts anti-angiogenesis effects via VEGFR-2 signaling pathway in breast cancer

Por Wang, Neng, Wang, Zhi-Yu, Mo, Sui-Lin, Loo, Tjing Yung, Wang, Dong-Mei, Luo, Hai-Bin, Yang, De-Po, Chen, Yu-Ling, Shen, Jian-Gang, Chen, Jian-Ping
Publicado em 2012