Ginsenoside Rg5 overcomes chemotherapeutic multidrug resistance mediated by ABCB1 transporter: in vitro and in vivo study

BACKGROUND: Multidrug resistance (MDR) to chemotherapy drugs remains a major challenge in clinical cancer treatment. Here we investigated whether and how ginsenoside Rg5 overcomes the MDR mediated by ABCB1 transporter in vitro and in vivo. METHODS: Cytotoxicity and colon formation as well as the int...

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Dettagli Bibliografici
Pubblicato in:J Ginseng Res
Autori principali: Feng, Sen-Ling, Luo, Hai-Bin, Cai, Liang, Zhang, Jie, Wang, Dan, Chen, Ying-Jiang, Zhan, Huan-Xing, Jiang, Zhi-Hong, Xie, Ying
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020
Soggetti:
Pharmacology and Physiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7031741/
https://ncbi.nlm.nih.gov/pubmed/32148406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jgr.2018.10.007
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