Ginsenoside Rg5 overcomes chemotherapeutic multidrug resistance mediated by ABCB1 transporter: in vitro and in vivo study

BACKGROUND: Multidrug resistance (MDR) to chemotherapy drugs remains a major challenge in clinical cancer treatment. Here we investigated whether and how ginsenoside Rg5 overcomes the MDR mediated by ABCB1 transporter in vitro and in vivo. METHODS: Cytotoxicity and colon formation as well as the int...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Ginseng Res
Prif Awduron: Feng, Sen-Ling, Luo, Hai-Bin, Cai, Liang, Zhang, Jie, Wang, Dan, Chen, Ying-Jiang, Zhan, Huan-Xing, Jiang, Zhi-Hong, Xie, Ying
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2020
Pynciau:
Pharmacology and Physiology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7031741/
https://ncbi.nlm.nih.gov/pubmed/32148406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jgr.2018.10.007
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