Dissecting the Structural Elements for the Activation of β-Ketoacyl-(Acyl Carrier Protein) Reductase from Vibrio cholerae

β-Ketoacyl-(acyl carrier protein) reductase (FabG) catalyzes the key reductive reaction in the elongation cycle of fatty acid synthesis (FAS), which is a vital metabolic pathway in bacteria and a promising target for new antibiotic development. The activation of the enzyme is usually linked to the f...

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Publicat a:J Bacteriol
Autors principals: Hou, Jing, Zheng, Heping, Chruszcz, Maksymilian, Zimmerman, Matthew D., Shumilin, Igor A., Osinski, Tomasz, Demas, Matt, Grimshaw, Sarah, Minor, Wladek
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2016
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719456/
https://ncbi.nlm.nih.gov/pubmed/26553852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00360-15
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