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Phosphorylation of the Mycobacterium tuberculosis β-Ketoacyl-Acyl Carrier Protein Reductase MabA Regulates Mycolic Acid Biosynthesis

Mycolic acids are key cell wall components for the survival, pathogenicity, and antibiotic resistance of the human tubercle bacillus. Although it was thought that Mycobacterium tuberculosis tightly regulates their production to adapt to prevailing environmental conditions, the molecular mechanisms g...

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Main Authors: Veyron-Churlet, Romain, Zanella-Cléon, Isabelle, Cohen-Gonsaud, Martin, Molle, Virginie, Kremer, Laurent
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857119/
https://ncbi.nlm.nih.gov/pubmed/20178986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.105189
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