The Mycobacterium tuberculosis β-Ketoacyl-Acyl Carrier Protein Synthase III Activity Is Inhibited by Phosphorylation on a Single Threonine Residue

Mycolic acids are hallmark features of the Mycobacterium tuberculosis cell wall. They are synthesized by the condensation of two fatty acids, a C(56-64)-meromycolyl chain and a C(24-26)-fatty acyl chain. Meromycolates are produced via the combination of type I and type II fatty acid synthases (FAS-I...

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Détails bibliographiques
Auteurs principaux: Veyron-Churlet, Romain, Molle, Virginie, Taylor, Rebecca C., Brown, Alistair K., Besra, Gurdyal S., Zanella-Cléon, Isabelle, Fütterer, Klaus, Kremer, Laurent
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2009
Sujets:
Protein Synthesis, Post-Translational Modification, and Degradation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649087/
https://ncbi.nlm.nih.gov/pubmed/19074144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806537200
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