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Immune activation of the host cell induces drug tolerance in Mycobacterium tuberculosis both in vitro and in vivo
Successful chemotherapy against Mycobacterium tuberculosis (Mtb) must eradicate the bacterium within the context of its host cell. However, our understanding of the impact of this environment on antimycobacterial drug action remains incomplete. Intriguingly, we find that Mtb in myeloid cells isolate...
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| Publicado no: | J Exp Med |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4854729/ https://ncbi.nlm.nih.gov/pubmed/27114608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151248 |
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