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Immune activation of the host cell induces drug tolerance in Mycobacterium tuberculosis both in vitro and in vivo
Successful chemotherapy against Mycobacterium tuberculosis (Mtb) must eradicate the bacterium within the context of its host cell. However, our understanding of the impact of this environment on antimycobacterial drug action remains incomplete. Intriguingly, we find that Mtb in myeloid cells isolate...
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| Опубликовано в: : | J Exp Med |
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| Главные авторы: | , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4854729/ https://ncbi.nlm.nih.gov/pubmed/27114608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151248 |
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