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Effectiveness of tuberculosis chemotherapy correlates with resistance to Mycobacterium tuberculosis infection in animal models

OBJECTIVES: It is widely believed that persistent Mycobacterium tuberculosis inhabits necrotic lung granulomas in humans and that the microenvironmental conditions encountered therein render the bacilli phenotypically tolerant to antibiotics, accounting for the long duration required for successful...

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Detalhes bibliográficos
Main Authors: Ahmad, Zahoor, Fraig, Mostafa M., Pinn, Michael L., Tyagi, Sandeep, Nuermberger, Eric L., Grosset, Jacques H., Karakousis, Petros C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3112031/
https://ncbi.nlm.nih.gov/pubmed/21602551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkr188
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